Hello everyone,
I think the best title are title number 1 and title number 4, as the have most of the elements of an appropriate title. Title number 1 has the intervention, the population and the comparison clearly stated, and title number 4 clearly states the type of study, the intervention and the population of the study.
The title number 5 is the worst of all in my opinion. I think from this title, only the population of interest is specified. The other elements of a topic are missing in this topic.
Jean Claude.